Blibiometric analysis of quercetin research from Scopus 2015–2025: effect lowering cholesterol on hypercholesterolemia in vivo study

Abstract

Quercetin is a flavonoid belonging to the flavanols class, widely found in fruits and vegetables. Research studies have investigated its biological activities, particularly its potential in reducing cholesterol levels. This study examined bibliometric analysis of quercetin research related to hypercholesterolemia using in vivo animal models based on Scopus data from 2015 to 2025. A total of 542 documents were retrieved using Boolean keywords. Bibliometric analysis was performed using R Studio and Biblioshiny to evaluate publication trends, contributing countries, leading institutions, authors, and keyword co-occurrences. The results indicate that China is the leading contributor, with Zhejiang Chinese Medical University as a prominent affiliation. The most frequent keywords include non-human, animal experiment, and controlled study. The findings highlight increasing research interest in quercetin as a natural compound for cholesterol management and emphasize the need for interdisciplinary collaboration.