Comparative analysis of dose distribution in phantom breast cancer: Enhancing radiative effects with gold particles under photon and electron beams

This paper was not presented at the conference.

Abstract

This paper was not presented at the conference.

The addition of particles with a large mass number known as radiosensitizer is widely used in radiotherapy to increase the dose to the target cancer. One of the widely chosen particles is gold. This study aimed to obtain information regarding the effect of adding gold particles on breast cancer using a Monte Carlo simulation. The research object used a breast cancer phantom composed of several materials: adipose, water, bone, lungs, and gold. The radiation energy used is 6 and 10 MeV photons, 6 and 9 MeV electrons. The results obtained are PDD curves, profile curves, and Dose Enhancement Ratio (DER). The PDD curve shows that the maximum dose of 100% in the phantom irradiated with 6 and 10 MeV photons and 6 and 9 MeV electrons is at a depth of 2,10 cm and 1,90 cm, respectively. The profile curve shows the correlation between the depth and the Full Width Half Maximum (FWHM) value which gets wider with a decrease in radiation dose. The maximum DER values for photons and electrons are at a depth of 2,10 cm and 1,90 cm, respectively, with a magnitude of 2,02% for 6 MeV photons, 3,45% for 10 MeV photons, 1,49% for 6 MeV electrons, and 1,46% for 9 MeV electrons.