Investigated of marine endophytic fungi Aspergillus terreus extract's antibacterial activity against Salmonella Typhimurium

This title will be presented on Friday, December 15, 2023 at 11.15 - 11.25 GMT+7.

Abstract

This title will be presented on Friday, December 15, 2023 at 11.15 - 11.25 GMT+7.

Efforts to control bacterial infectious diseases carried out by giving natural antibacterial. One of natural antibacterial sources is marine fungi including algae extracts and mangrove leaves. The aim of study was analyzed the antibacterial properties of endophytic marine fungi Aspergillus terreus extract against Salmonella typhimurium. The methods used in this study include cultivation, extraction, antibacterial test, fractionated using TLC, and bioautography. The data obtained were analyzed descriptively. The result showed that the Aspergillus terreus isolates that cultivated on the 9 day have maximum antibacterial activity around 8.88 mm (level 2 mg), 6.61 mm (level 1 mg), and 4.91 mm (level 0.5 mg). The active compounds contained in the extract of Aspergillus terreus were steroids, phenols, and flavonoids. Fractionation with TLC and bioautography showed an inhibitory zone of Aspergillus terreus was 17.7 mm at Rf values of 0.9, 0.83 (λ= 254 nm) or 0.8 (λ= 366 nm). In conclusion, Aspergillus terreus as marine fungi from mangrove leaves that cultivated for 9 days had a largest diameter of inhibition zone 8.88 mm (level 2 mg). The active compounds of fungi were steroids, phenols, and flavonoid