Study of candidate genes associated with growth trait in local chickens

Abstract

Local chickens are pure native chickens or chickens developed for certain purposes while maintaining their original superior characteristics. The potential of local chickens can be developed according to breeding objectives, one of which is effort to improve economic traits such as growth traits. This study aims to identify major gene candidates associated with growth traits in local chickens. This research was conducted by a literature study of data from previous publications to obtain a list of major candidate genes associated with local chicken growth traits. The literature review was conducted using Rayyan AI and candidate genes were clustered into growth-related traits using Venn Diagram. The selected traits were body weight and body morphometrics. The results showed that 13 candidate genes have been studied in local chickens. Three genes were selected as candidates because they have associations with both growth-related traits. Three candidate genes are Growth Hormone (GH), Insuline-like Growth Factor 2 (IGF2), and Thyroid-Stimulating Hormone Beta Subunit (TSHB). There were nine others genes that only have association one trait (body weight/morphometrics only), while one gene hasn’t association (IGFBP2). Three selected genes can be used as molecular markers and association studies with growth traits in local chickens need to be conducted.